Cellulose-Based Nanofibers in Wound Dressing

Cellulose-based nanofibers are emerging as a promising material for wound dressings due to their biodegradability, biocompatibility, and structural similarity to the extracellular matrix. These nanofibers, derived from the abundant biopolymer cellulose, can be processed into films, fibers, and membranes with tailored properties. Surface modifications with nanoparticles or bioactive compounds enhance their antimicrobial properties and support sustained drug release, crucial for chronic wound infections. Modern fabrication techniques like electrospinning allow precise control over fiber morphology and drug delivery characteristics. This review emphasizes the potential of cellulose nanofibers as a sustainable, multifunctional platform for advanced wound dressings, offering improved healing, reduced scarring, and integration with drug delivery and tissue engineering approaches.