Contrast-Enhanced Ultrasound Evaluation of Canine Prostatic Hyperplasia Before and After Osaterone Acetate Therapy: Preliminary Results

    June 2024 in “ Animals
    Giorgia Pettina, Roberta Bucci, Antonio Mazzetti, Marco Quartuccio, Domenico Robbe, Maria Carmela Pisu
    TLDR Osaterone acetate reduces prostate size and enzyme levels in dogs with benign prostatic hyperplasia.
    This study investigates the effects of osaterone acetate (OSA) treatment on benign prostatic hyperplasia (BPH) in 15 dogs using contrast-enhanced ultrasonography (CEUS). The study measures canine prostate-specific esterase (CPSE) levels and prostate volume before and after treatment. Results show significant reductions in CPSE and prostate volume after 21 days of OSA treatment, with increased wash-in and wash-out times of the contrast agent, indicating reduced prostatic perfusion. These preliminary findings suggest that CEUS is a promising tool for monitoring BPH in dogs.
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