TLDR Chemotherapy causes hair loss, nausea, fatigue, and blood issues, but counseling can help manage these effects.
The study observed 50 female carcinoma breast patients undergoing chemotherapy to assess the prevalence and severity of chemotoxicities. Hair loss was prevalent in 98% of patients with increasing severity, while nausea and vomiting were experienced by 100% and 54% of patients, respectively, with a decreasing trend in severity. Fatigue was universally experienced with increasing severity, and leukopenia and thrombocytopenia were noted multiple times in several patients. No significant differences in toxicity were found between chemotherapy regimens, and severe chemotoxicity was minimal. The findings suggested that proper patient counseling on these adverse effects could mitigate their impact on quality of life.
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June 2023 in “Molecules/Molecules online/Molecules annual” Cepharanthine has many medicinal uses but needs improvement for better effectiveness.
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July 1996 in “Annals of Internal Medicine” Itraconazole may cause low platelet and white blood cell counts.
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March 2004 in “Annals of oncology” Pegylated liposomal doxorubicin is as effective as conventional doxorubicin but causes fewer heart problems and side effects.
December 2025 in “Cell Communication and Signaling” The study investigates the potential of minoxidil, a common hair growth treatment, as a therapeutic agent for myelodysplastic syndrome (MDS) by targeting the Wnt4 signaling pathway. Using zebrafish models, minoxidil was found to suppress the proliferation of hematopoietic stem and progenitor cells (HSPCs) without causing apoptosis, alleviating MDS-like symptoms while minimizing adverse effects. The effects were consistent in vitro with human malignant hematopoietic cells and in vivo in mice, where lower doses minimized hematopoietic toxicity. The study highlights Wnt4 as a novel target for MDS treatment and supports the repurposing of minoxidil for hematopoietic disorders, suggesting its potential to selectively modulate abnormal progenitor proliferation while sparing normal hematopoiesis.
May 1993 in “Current problems in dermatology” Skin symptoms are important for diagnosing infections in children.
