Chemotherapy-Induced Alopecia in Ovarian Cancer: Incidence, Mechanisms, and Impact Across Treatment Regimens

January 2025 in “ Cancers ”

Simonetta I. Gaumond, Gabriela E Beraja, Isabella Kamholtz, Lina M. Ferrari, Rami H. Mahmoud, Joaquín J. Jiménez

chemotherapy-induced alopecia alopecia ovarian cancer cancer therapy

TLDR Improving treatment plans can reduce hair loss and improve life quality for ovarian cancer patients.

Chemotherapy-induced alopecia (CIA) significantly affects the psychosocial well-being of ovarian cancer patients. The document emphasizes the importance of optimizing treatment protocols to minimize the severity of alopecia while maintaining the effectiveness of cancer therapy. The insights provided could inform future therapeutic strategies aimed at enhancing patient outcomes and quality of life.

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Research cited in this study

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research Prevention and Treatment of Chemotherapy-Induced Alopecia: What Is Available and What Is Coming?

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Cancer treatments often cause hair disorders, significantly affecting patients' quality of life, and better management methods are needed.

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research Chemotherapy-Induced Alopecia Management: Clinical Experience and Practical Advice

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The conclusion is to use scalp cooling, gentle hair care, and treatments like minoxidil for managing hair loss from chemotherapy, and stresses the need for more research and collaboration in this area.

research Pathobiology of Chemotherapy-Induced Hair Loss

218 citations , January 2013 in “The Lancet Oncology”

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

research Chemotherapy-Induced Hair Loss

48 citations , September 2010 in “PubMed”

Chemotherapy often causes hair loss, which is distressing for many, but usually reversible.

research Docetaxel and Oxaliplatin in the Second-Line Treatment of Platinum-Sensitive Recurrent Ovarian Cancer: A Phase II Study

29 citations , August 2007 in “Annals of Oncology”

Docetaxel and oxaliplatin are effective and have manageable side effects for recurrent platinum-sensitive ovarian cancer.

research Recurring Chemotherapy-Associated Alopecia Areata: Case Report and Literature Review

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Chemotherapy may cause recurring hair loss due to an autoimmune response.

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research Mucocutaneous Reactions to Chemotherapy

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Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

research Hair Disorders in Patients with Cancer

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Cancer treatments often cause hair disorders, significantly affecting patients' quality of life, and better management methods are needed.

Management of Alopecia Due to Cancer Therapies

Chemotherapy-Induced Alopecia in Ovarian Cancer: Incidence, Mechanisms, and Impact Across Treatment Regimens

Research cited in this study

research Prevention and Treatment of Chemotherapy-Induced Alopecia: What Is Available and What Is Coming?

research Hair Loss During and After Breast Cancer Therapy

research CDK4/6 Inhibition Mitigates Stem Cell Damage in a Novel Model for Taxane-Induced Alopecia

research Hair Disorders in Patients with Cancer

research The Side Effects of Platinum-Based Chemotherapy Drugs: A Review for Chemists

research Chemotherapy-Induced Alopecia Management: Clinical Experience and Practical Advice

research Pathobiology of Chemotherapy-Induced Hair Loss

research Chemotherapy-Induced Hair Loss

research Docetaxel and Oxaliplatin in the Second-Line Treatment of Platinum-Sensitive Recurrent Ovarian Cancer: A Phase II Study

research Recurring Chemotherapy-Associated Alopecia Areata: Case Report and Literature Review

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