Cicatricial Alopecia Secondary to Radiation Therapy: Case Report and Review of the Literature

The document discussed cicatricial alopecia resulting from high-dose radiation therapy (RT) used to treat intracranial malignancies, which can permanently destroy hair follicles and lead to permanent alopecia. A case was reported where radiation-induced cicatricial alopecia was confirmed by histopathology without obvious clinical scarring or dermal fibrosis, making the patient a good candidate for hair transplantation. The study suggested that if the radiation dose is kept under 16 Gy at a depth of 5 mm, the incidence of radiation-induced cicatricial alopecia could be avoided or significantly reduced.