Cicatricial Alopecia/Lichen Planopilaris: The Cleveland Clinic Foundation Experience on Evaluation, Diagnosis, and Treatment
March 2004
in “
Journal of the American Academy of Dermatology
”
cicatricial alopecia lichen planopilaris follicular hyperkeratosis pruritus perifollicular erythema scalp pain lichen planus ferritin ketoconazole shampoo topical steroids intralesional steroids biotin scalp reduction surgery hair transplant surgery Nizoral steroid injections hair transplant hair surgery
TLDR Middle-aged women with cicatricial alopecia/lichen planopilaris responded well to treatments like ketoconazole shampoo and steroids.
The study reviewed 29 patients with cicatricial alopecia/lichen planopilaris at The Cleveland Clinic Foundation, predominantly affecting middle-aged women. The condition was characterized by symptoms such as follicular hyperkeratosis, pruritus, perifollicular erythema, and scalp pain, with lichen planus involvement in some cases. Nutritional abnormalities, particularly low normal ferritin levels, were noted in a subset of patients. Treatment primarily involved ketoconazole shampoo, topical and intralesional steroids, and Biotin, with positive responses observed in the active perimeter of alopecic patches. Scalp reduction and hair transplant surgeries were suggested for the inactive end stage to manage the affected area or enhance hair density.
