Efficacy and Safety of Cinainu in Pediatric Alopecia Areata: An International, Double-Blind, Randomized, Placebo-Controlled, Phase II/III Trial

July 2025 in “ British Journal of Dermatology ”

Ulrike Blume‐Peytavi, Bianca Maria Piraccini, Pascal Reygagne, Julien Guiraud, B.N. Mukherjee, A Guichard, Jiawei Liu, William Pralong, Saad Harti

Cinainu alopecia areata paediatric alopecia areata

TLDR Cinainu is effective and safe for treating children's alopecia areata.

The study evaluated the efficacy and safety of Cinainu in treating children and adolescents with moderate-to-severe alopecia areata (AA) through an international, double-blind, randomized, placebo-controlled, phase II/III trial. The results demonstrated that Cinainu was effective and safe, providing sustained benefits during follow-up for this population, which has significant unmet needs.

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Research cited in this study

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Topical corticosteroids are the best initial treatment for children's alopecia areata.

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Alopecia areata treatment varies, with no optimal method established yet.

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Topical botanical lotion increases hair density and improves quality of life in women with hair loss.

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A botanical lotion can increase scalp collagen and extend hair growth phase, potentially improving hair thinning issues.

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