Clinical and Biochemical Characteristics in PCOS Women With Menstrual Abnormalities

    December 2016 in “ PubMed ”
    Vasiliki Christodoulopoulou, Eftihios Trakakis, Vasilios Pergialiotis, Μelpomeni Peppa, Charalampos Chrelias, Dimitrios Kassanos, Nikolaos Papantoniou
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    TLDR Menstrual abnormalities in PCOS women may not greatly affect their metabolic and hormonal profile.
    In 2016, a study involving 309 women with Polycystic Ovary Syndrome (PCOS) aged 17-35 years found that 72.2% had menstrual cycle disorders. These women had significantly higher levels of Luteinizing Hormone (LH) and Thyroid Stimulating Hormone (TSH), lower levels of prolactin, and elevated fasting glucose compared to those with normal menstrual cycles. However, markers of insulin resistance did not differ. The study also found that 15.1% of the women were overweight, 24% were obese, 36% had androgenetic alopecia, and 56.4% had acne. Despite these findings, the study concluded that menstrual cycle abnormalities might not significantly influence the metabolic and hormonal profile of PCOS patients.
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