Clinical and Hematological Studies on Experimentally Induced Selenosis in Crossbred Cow Calves

The study investigated the effects of sodium selenite-induced subacute and chronic selenosis on clinical and hematological parameters in crossbred cow calves. Subacute selenosis was induced with a dose of 2.5 mg/kg for 21 days, while chronic selenosis was induced with 0.25 mg/kg for 16 weeks. Subacute toxicity symptoms included anorexia, salivation, eye redness, joint swelling, and labored breathing, while chronic toxicity symptoms included rough hair coat, alopecia, hoof enlargement, and tail gangrene. Both forms of selenosis significantly affected blood parameters such as hemoglobin, packed cell volume, and total erythrocyte and leukocyte counts, with chronic toxicity also altering mean corpuscular volume and hemoglobin. Erythrocyte sedimentation rate and mean corpuscular hemoglobin concentration were not significantly affected.