Clinical Profile and Outcomes of Patients With Systemic Lupus Erythematosus

    September 2024 in “ Cureus ”
    Prasad Chandrakant Bagare, Akshata Borle, Priya Baluni, Gayatri Ekbote, Shashikala Sangale
    TLDR Early detection and targeted management are crucial for better outcomes in systemic lupus erythematosus.
    This study on systemic lupus erythematosus (SLE) involved 80 patients, predominantly young females, with a mean age of 29.4 years. It highlighted diverse clinical manifestations, with common symptoms including oral ulcers (98.75%) and alopecia (95%). Renal involvement was significant, affecting 50% of patients, and anemia was prevalent in 66.25%. Autoantibody profiles showed high ANA (98.8%) and DsDNA (61.3%) positivity. Over 68% of patients achieved remission, while 16.3% experienced organ damage. The study emphasizes the importance of early detection and targeted management, particularly for renal and mucocutaneous symptoms, and suggests future research on disease progression and treatment strategies.
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