Correlation of Clinical and Trichoscopy Features With the Degree of Histologic Inflammation in Lichen Planopilaris and Frontal Fibrosing Alopecia in a Cross-Sectional Study

This study investigated the correlation between clinical and trichoscopic features with histologic inflammation in lichen planopilaris (LPP) and frontal fibrosing alopecia (FFA) over 5 years, involving 103 patients, of which 94 were confirmed with LPP or FFA. The study found no positive correlation between clinical/trichoscopic findings and the degree of histologic inflammation, indicating that clinical variables do not accurately represent disease activity at the histopathologic level. The study suggests that experienced dermatopathologist opinions and microscopic field methods are reliable for assessing inflammation intensity, which is crucial for diagnosis and management, as clinical signs do not translate to histopathologic inflammation.