Cognitive Effects of Testosterone and Finasteride Administration in Older Hypogonadal Men

    August 2014 in “ PubMed
    Stephen E. Borst, Joshua F. Yarrow, Carmen Fernandez, Christine F. Conover, Fan Ye, John R. Meuleman, Matthew P. Morrow, Baiming Zou, Jonathan J. Shuster
    Image of study
    TLDR Testosterone improves mood and thinking skills; finasteride has no effect.
    The study investigated the cognitive effects of testosterone and finasteride administration in older hypogonadal men. The results showed that testosterone administration produced small improvements in depressive symptoms and visuospatial cognition, while finasteride administration did not have any significant effects on cognitive function. The study suggests that testosterone replacement therapy may have cognitive benefits for older men with hypogonadism, but further research is needed to explore the potential benefits in other cognitive domains.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 1000+ results

      community I’m considering stopping finasteride

      in Finasteride/Dutasteride  149 upvotes 2 days ago
      The user is considering stopping finasteride due to depression, anxiety, and difficulty building muscle, despite its effectiveness in stopping hair loss. Suggestions include reducing the dose, switching to topical solutions, or consulting a doctor for alternatives like dutasteride or RU58841.

      community 25 years on finasteride - my experience

      in Finasteride/Dutasteride  946 upvotes 11 months ago
      A long-term finasteride user experienced side effects like sexual dysfunction, dry eyes, muscle weakness, and brain fog, which improved when they stopped the medication. They decided to stop finasteride again, questioning if maintaining hair was worth the negative impact on their well-being.

      community My Estradiol Level on Finasteride

      in Research/Science  18 upvotes 6 months ago
      Finasteride has no effect on the user's estradiol levels, and body fat may influence aromatization. The user is on testosterone replacement therapy and uses everyday injections to manage high RBC count, with plans to measure DHT, DHEA-S, and pregnenolone levels.

      community 5 months 0.5mg fin daily and minoxidil 5% once daily

      in Progress Pictures  32 upvotes 3 weeks ago
      The user experienced significant hair regrowth and increased confidence after using 0.5mg finasteride daily and 5% minoxidil once daily for five months, with no side effects reported. Other users shared similar experiences, discussing libido changes and considering testosterone replacement therapy (TRT).

    Related Research

    1 / 1 results