Low-Molecular-Weight Collagen Peptides Improve Hair Health in Adults with Damaged Hair: A Randomized, Double-Blind, Placebo-Controlled Trial

January 2026 in “ International Journal of Peptide Research and Therapeutics ”

Yu-ri Gwon, A Reum Kim, Mi Hye Seo, Ji-Hae Lee, Ji Eun Lee, Hae Kwang Lee, Byung Cheol Park, Joon Seok, Beom Joon Kim, J. H. Kim, Miyoung Park

low-molecular-weight collagen peptides collagen supplement GPVGPS Collagen hair luster shaft surface integrity tensile strength hair diameter hair density collagen peptides collagen

TLDR Collagen supplements improve hair health and are safe.

A study involving 100 adults aged 19-60 with mild-to-moderate hair damage assessed the effects of a low-molecular-weight collagen peptide supplement (GPVGPS Collagen®) on hair health. Participants were randomized to receive either 2,000 mg/day of the collagen supplement or a placebo for 24 weeks. Results showed that the collagen group experienced significant improvements in hair luster, shaft surface integrity, tensile strength, diameter, and density compared to the placebo group. Participants also reported higher satisfaction with their hair condition. No safety-related adverse events were observed, indicating that GPVGPS Collagen® is both effective and safe for enhancing hair health.

View this study on link.springer.com →

Discuss this study in the Community →

Research cited in this study

10 / 10 results

Gly-Pro-Val-Gly-Pro-Ser Low Molecular Weight Fish Collagen Peptide Promotes Hair Regeneration in Human Dermal Papilla Cells and C57BL/6 Mice

research Gly-Pro-Val-Gly-Pro-Ser Low Molecular Weight Fish Collagen Peptide Promotes Hair Regeneration in Human Dermal Papilla Cells and C57BL/6 Mice

December 2025 in “PubMed”

Fish collagen peptide may boost hair growth and health.

Revealing Novel Insights on How Oral Supplementation With Collagen Peptides May Prevent Hair Loss: Lessons From the Human Hair Follicle Organ Culture

research Revealing Novel Insights on How Oral Supplementation With Collagen Peptides May Prevent Hair Loss: Lessons From the Human Hair Follicle Organ Culture

March 2024 in “Journal of functional foods”

Collagen peptides from marine and bovine sources may help prevent hair loss by affecting hair follicle stem cells differently.

Efficacy and Tolerability of an Oral Supplement Containing Amino Acids, Iron, Selenium, and Marine Hydrolyzed Collagen in Subjects With Hair Loss: A Prospective, Randomized, 3-Month, Controlled, Assessor-Blinded Study

research Efficacy and Tolerability of an Oral Supplement Containing Amino Acids, Iron, Selenium, and Marine Hydrolyzed Collagen in Subjects With Hair Loss: A Prospective, Randomized, 3-Month, Controlled, Assessor-Blinded Study

June 2023 in “Skin Research and Technology”

The supplement with amino acids, iron, selenium, and marine hydrolyzed collagen improved hair growth more than drug treatment alone, with most people tolerating it well.

research Integrative and Mechanistic Approach to the Hair Growth Cycle and Hair Loss

104 citations , January 2023 in “Journal of Clinical Medicine”

A holistic approach is needed to effectively address hair loss by understanding and influencing the hair growth cycle.

research Morphogenesis, Growth Cycle, and Molecular Regulation of Hair Follicles

21 citations , May 2022 in “Frontiers in Cell and Developmental Biology”

Hair growth and health are influenced by factors like age, environment, and nutrition, and are controlled by various molecular pathways. Red light can promote hair growth, and understanding these processes can help treat hair-related diseases.

research Twelve-Point Scale Grading System of Scanning Electron Microscopic Examination to Investigate Subtle Changes in Damaged Hair Surface

8 citations , January 2016 in “Skin research and technology”

The 12-point scale is better for evaluating small changes in hair condition after using hair care products.

research Age-Dependent Changes in Damage Processes of Hair Cuticle

20 citations , January 2015 in “Journal of cosmetic dermatology”

Older people's hair cuticles get more easily damaged and lose protective oils, especially in their 40s and 50s.

research Photoaggravation of Hair Aging

24 citations , January 2009 in “International Journal of Trichology”

Sunlight exposure ages hair, making it brittle, stiff, and dry.

research Hair Shaft Abnormalities: Clues to Diagnosis and Treatment

44 citations , January 2005 in “Dermatology”

Hair problems can be caused by genetics or the environment, and treatment should focus on the cause and reducing hair damage.

research Photoaging of Hair Fiber and Photoprotection

18 citations , January 1994 in “Skin pharmacology and physiology”

Sunlight damages hair, causing cuticle loss, protein changes, and discoloration.

Similar Research

5 / 1000+ results

research Calcium and Vitamin D Supplementation With and Without Collagen on Bone Density and Skin Elasticity in Menopausal Women—A Randomized Controlled Study

September 2025 in “Clinics and Practice”

Collagen with calcium and vitamin D improves bone health, skin elasticity, and reduces hair loss in menopausal women.

research Clinical Efficacy of Silk Sericin Dressing with Collagen for Split-Thickness Skin Graft Donor Site Treatment

January 2021

Silk sericin dressing with collagen heals wounds faster and improves scar quality better than Bactigras.

research How Oral Collagen Intake Can Be Useful in Dermatology

1 citations , June 2018 in “Ukrainian Journal of Dermatology Venerology Cosmetology”

Oral collagen improves skin, nails, hair, and reduces cellulite.

research Hair-Growth-Promoting Effects of the Fish Collagen Peptide in Human Dermal Papilla Cells and C57BL/6 Mice Modulating Wnt/Beta-Catenin and BMP Signaling Pathways

October 2022 in “International Journal of Molecular Sciences”

Fish collagen peptides can significantly promote hair growth.

research Collagen Hydrolysate from Mozambique Tilapia Scales Improves Hair and Skin Health

2 citations , August 2023 in “Marine drugs”

Collagen from tilapia scales may improve hair and skin health by reducing stress and inflammation and encouraging hair growth.