Medical Comorbidities and Sex Distribution Among Patients With Lichen Planopilaris and Frontal Fibrosing Alopecia: A Retrospective Cohort Study

August 2020 in “ Journal of the American Academy of Dermatology ”

Megan H. Trager, Jonathan Lavian, Eunice Y. Lee, Dahsan Gary, Fabian Jenkins, Angela M. Christiano, Lindsey A. Bordone

TLDR Women with lichen planopilaris and frontal fibrosing alopecia often have other health issues like hypothyroidism and lupus.

This retrospective cohort study at Columbia University Irving Medical Center analyzed 376 patients with lichen planopilaris (LPP) and frontal fibrosing alopecia (FFA), revealing a strong female predominance, with odds ratios of 1.99 for LPP and 8.60 for FFA. Patients with these conditions were more likely to have comorbidities such as hypothyroidism, psoriasis, systemic lupus erythematosus, vitiligo, and lichen planus, but were less likely to have diabetes mellitus. The study emphasized the need for larger prospective studies to explore these associations further and acknowledged limitations due to its retrospective design and reliance on ICD codes for assessing comorbidities.

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Research cited in this study

2 / 2 results

research Comorbid Conditions in Lichen Planopilaris: A Retrospective Data Analysis of 334 Patients

21 citations , September 2018 in “International journal of women’s dermatology”

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research Medical Comorbidities in Patients with Lichen Planopilaris: A Retrospective Case-Control Study

19 citations , April 2018 in “International Journal of Dermatology”

People with Lichen Planopilaris are more likely to have autoimmune diseases, especially Systemic Lupus Erythematosus, and less likely to have diabetes and some other common conditions.

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