Congenital Lipedematous Alopecia in a 6-Year-Old Asian Boy

This article reports the first known case of congenital lipedematous alopecia (LA) in a male, specifically a 6-year-old Asian boy. LA is characterized by scalp thickening and non-scarring alopecia, with a significant female preponderance. The boy exhibited patchy hair loss since birth, with a soft, spongy scalp texture and thickened subcutaneous adipose tissue. Histopathological examination showed capillary and lymphatic dilation and a reduced number of hair follicles. Despite no medical treatment, minor improvement was observed over 3 years. The pathogenesis of LA is unclear, though genetic factors and sex hormones may play roles. There is no established treatment, but spontaneous hair growth has been noted in some cases. Further research is needed to understand the disease mechanism and develop effective therapies.