Chronic Telogen Effluvium and Female Pattern Hair Loss Are Separate and Distinct Forms of Alopecia: A Histomorphometric and Immunohistochemical Analysis

August 2014 in “ Clinical and Experimental Dermatology ”

Carla Bittencourt, D. A. Ferraro, Taís Cristina Bastos Soares, Arthur Moraes, Maria Letícia Cintra

chronic telogen effluvium female pattern hair loss alopecia histomorphometric analysis immunohistochemical analysis telogen release cycle synchronization anagen follicular mitotic rates hair miniaturization CTE FPHL

TLDR CTE and FPHL are different hair loss types with unique causes.

The study aimed to differentiate between chronic telogen effluvium (CTE) and female pattern hair loss (FPHL) through histomorphometric and immunohistochemical analysis. The results showed that CTE is a distinct disorder from FPHL, with different pathogenic mechanisms. CTE is related to immediate telogen release, leading to cycle synchronization, while FPHL is related to accelerated anagen follicular mitotic rates, resulting in hair miniaturization. The study adds to the understanding of the pathogenesis of these conditions, which is important for therapeutic tests.

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Research cited in this study

13 / 13 results

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CTE can distort results in hair growth trials, so exclude it carefully.

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Middle-aged women with chronic telogen effluvium experience increased hair shedding but usually don't get significantly thinner hair.

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Chronic Telogen Effluvium is a hair loss condition in middle-aged women that usually doesn't lead to complete baldness.

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