Curly Bare (Cub), a New Mouse Mutation on Chromosome 11 Causing Skin and Hair Abnormalities, and a Modifier Gene (Mcub) on Chromosome 5

    January 2003 in “ Genomics
    Kenneth R. Johnson, PRISCILLA W. LANE, Susan A. Cook, Belinda S. Harris, Patricia F. Ward‐Bailey, Roderick T. Bronson, Bonnie Lyons, Leonard D. Shultz, Muriel T. Davisson
    TLDR A new mouse mutation causes skin and hair issues, influenced by another gene.
    The study identified a new mouse mutation called "curly bare" (cub) on chromosome 11, which caused skin and hair abnormalities. Additionally, a modifier gene (mcub) on chromosome 5 was found to influence the expression of these abnormalities. The research provided insights into the genetic basis of hair and skin conditions, although it was conducted on mice and may not directly translate to humans. The findings contributed to the understanding of genetic interactions affecting hair and skin phenotypes.
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