The Current Treatments and Perspectives for Androgenetic Alopecia

In 2009, the primary treatments for androgenetic alopecia (AGA) were finasteride and minoxidil, both of which had proven efficacy and safety. Finasteride, an oral medication, was shown to significantly reduce scalp and serum DHT levels, improving hair growth by inhibiting the enzyme 5α-reductase type II. Minoxidil, a topical stimulant originally used for blood pressure control, was effective in increasing hair count, although its exact mechanism was unclear. Other treatments like dutasteride and various topical agents were also mentioned, but the document highlighted the necessity for evidence-based information to counteract unsubstantiated market claims. The Japanese Dermatological Association was preparing AGA treatment guidelines, set to be released in 2009.