Cardiovascular Risk in Patients with Scarring and Non-Scarring Alopecias: Assessing the Current State of Evidence

    Sally R. Frenkel, Camille Robinson, Michael Garshick, Seth J. Orlow, Kristen Lo Sicco
    TLDR Alopecia, especially androgenic, may increase cardiovascular risk, but more research is needed.
    The document reviews existing literature on the association between alopecia and cardiovascular disease (CVD), focusing on androgenic alopecia (AGA) and alopecia areata (AA). It finds that AGA is associated with cardiovascular risk factors such as hypertension, dyslipidemia, and insulin resistance, as well as coronary artery disease. For AA, studies suggest a correlation with CVD risk, though not always statistically significant. Research on scarring alopecias and their CV risk is limited and often contradictory. The conclusion emphasizes the need for more robust studies, particularly on cicatricial alopecias, to fill the gap in understanding the link between alopecia and CVD.
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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 3 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community scarring alopecia awareness in this community

      in Chat  33 upvotes 3 years ago
      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

      community How essential is scalp biopsy when dealing with hair loss?

      in Treatment  6 upvotes 1 year ago
      The user experienced hair loss despite using Fin and Min for 12 years and switched to Dutasteride, RU58841, and Keto scalp serum, but shedding and itch persist. They are considering increasing Dutasteride to 2.5mg and questioning the necessity of a scalp biopsy, with mixed opinions on its usefulness.

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