Cyclosporine A-Induced Intracranial Thrombotic Complications: Systematic Review and Case Report

    February 2021 in “ Frontiers in Neurology ”
    Siying Song, Zhongao Wang, Yuchuan Ding, Xunming Ji, Ran Meng
    TLDR Cyclosporine-A can cause serious blood clots in the brain, so patients need careful monitoring.
    The document reviewed cases and literature on cyclosporine-A (CsA)-induced intracranial thrombotic complications, particularly cerebral venous thrombosis (CVT). It highlighted that CsA, an immunosuppressive drug, was associated with increased thrombotic risks, especially in patients with aplastic anemia (AA) and those undergoing renal transplantation. The review identified 79 articles involving 706 patients and found that CsA-induced thrombosis could affect arteries, veins, and capillaries, with renal vascular damage being most common. The study emphasized the need for careful monitoring of thrombotic events in patients treated with CsA and called for further research to understand its prothrombotic effects.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 24 results

      community Forgotten 'Total Revival' Stack

      in Research/Science  42 upvotes 9 months ago
      Cyclosporine A is discussed as a powerful hair growth stimulant, potentially more effective than minoxidil, but concerns about safety and side effects, including cancer risk, limit its use. The conversation highlights the need for further research and experimentation with topical application, despite its risks.

      community The DEFINITIVE cure for hairloss

      in Satire  270 upvotes 8 months ago
      The conversation humorously suggests using immunosuppressants like ciclosporine and oral minoxidil for hair regrowth, with a satirical plan involving hair transplants from family members. It highlights the side effects and impracticality of such treatments, emphasizing the post's satirical nature.

      community Starting Way-316606 for the first time today.

      in Research/Science  30 upvotes 11 months ago
      A user is experimenting with a homemade solution of WAY-316606 for hair regrowth, combining it with other treatments like minoxidil and dutasteride. The community expresses concern over the safety and mental health implications of such drastic measures, with mixed opinions on the effectiveness of WAY-316606.

    Similar Research

    5 / 1000+ results