Dab2 (Disabled-2), an adaptor protein, regulates self-renewal of hair follicle stem cells
May 2024
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Communications Biology
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Research cited in this study
18 / 18 resultsresearch SIRT7 Activates Quiescent Hair Follicle Stem Cells to Ensure Hair Growth in Mice
SIRT7 protein is crucial for starting hair growth in mice.
research Context-Dependent Effect of sPLA2-IIA Induced Proliferation on Murine Hair Follicle Stem Cells and Human Epithelial Cancer
sPLA2-IIA increases growth in hair follicle stem cells and cancer cells, suggesting it could be targeted for hair growth and cancer treatment.
research Extracellular Proteoglycan Decorin Maintains Human Hair Follicle Stem Cells
Decorin helps keep hair follicle stem cells and may prevent age-related hair loss.
research Baicalin Increases Hair Follicle Development by Enhancing Canonical Wnt/β-Catenin Signaling and Activating Dermal Papilla Cells in Mice
Baicalin helps hair growth by activating specific cell signals and pathways.
research sPLA2-IIA Overexpression in Mice Epidermis Depletes Hair Follicle Stem Cells and Induces Differentiation Mediated Through Enhanced JNK/c-Jun Activation
Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.
research Hair Follicle Aging Is Driven by Transepidermal Elimination of Stem Cells via COL17A1 Proteolysis
Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.
research Regenerative Hair Waves in Aging Mice and Extra-Follicular Modulators Follistatin, Dkk1, and Sfrp4
Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.
research Spatial Organization Within a Niche as a Determinant of Stem-Cell Fate
research Competitive Balance of Intrabulge BMP/Wnt Signaling Reveals a Robust Gene Network Ruling Stem Cell Homeostasis and Cyclic Activation
BMP and Wnt signaling balance controls hair follicle stem cell activity and hair growth.
research Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration
Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.
research Hair Follicle Stem Cells Provide a Functional Niche for Melanocyte Stem Cells
COL17A1 is crucial for preventing hair graying and loss by supporting hair and pigment stem cells.
research Bald Scalp in Men with Androgenetic Alopecia Retains Hair Follicle Stem Cells but Lacks CD200-Rich and CD34-Positive Hair Follicle Progenitor Cells
Men with baldness due to androgenetic alopecia still have hair stem cells, but lack specific cells needed for hair growth.
research The Hair Follicle as a Dynamic Mini-Organ
Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
research Nfatc1 Balances Quiescence and Proliferation of Skin Stem Cells
NFATc1 controls hair stem cell activity, affecting hair growth and could be a target for hair loss treatments.
research Defining the Impact of Beta-Catenin/Tcf Transactivation on Epithelial Stem Cells
β-catenin is essential for stem cell activation and proliferation in hair follicles.
research Expression of ΔNLef1 in Mouse Epidermis Results in Differentiation of Hair Follicles into Squamous Epidermal Cysts and Formation of Skin Tumors
Overexpression of ΔNLef1 in mouse skin leads to hair loss, cysts, and skin tumors.
research Expression of Calcium-Binding S100 Proteins A4 and A6 in Regions of the Epithelial Sac Associated with the Onset of Hair Follicle Regeneration
S100A4 and S100A6 proteins may activate stem cells for hair follicle regeneration and could be potential targets for hair loss treatments.
research WNT Signaling in the Control of Hair Growth and Structure
The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.
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5 / 5 results
research Optimization of Hair Follicle Spheroids for Hair-On-A-Chip
The method could grow hair in lab settings without using animals.
research Skin-On-A-Chip Strategies For Human Hair Follicle Regeneration
New technologies show promise for better hair regeneration and treatments.
research Tissue Engineered Human Hair Follicles from Genetically, Environmentally, and Extrinsically Reprogrammed Dermal Papilla Cells
Researchers developed a method to grow human hair follicles using 3D-printed skin models and modified cells.
research Keratins of the Human Hair Follicle
More research is needed to understand how hair keratins work and their role in hair disorders.
research Trans-Species Hair Growth Induction by Human Hair Follicle Dermal Papillae
Human hair follicle cells can grow hair when put into mouse skin if they stay in contact with mouse cells.