TLDR Male hypogonadism affects skin and hair, causing thin skin, less hair, and skin reactions to treatment.
Male hypogonadism was associated with several dermatological features due to its androgen-dependent nature. Patients exhibited thin skin with increased wrinkles, reduced hair growth in various areas, and a lack of pigmentation in genital skin. Prepubertal hypogonadism did not lead to severe acne but resulted in sebostasis. Typical androgenetic alopecia was not observed. Treatment for hypogonadism could cause dermatological diseases, with irritative or allergic skin reactions being common, particularly with non-scrotal transdermal testosterone systems. Although various syndromes included dermatological symptoms linked to male hypogonadism, their prevalence was low.
18 citations
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January 2001 in “Annual Reports in Medicinal Chemistry” Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.
January 2003 in “Journal für Kardiologie (Krause & Pachernegg GmbH)” Testosterone therapy can improve skin and hair in men with low testosterone but may cause skin irritation with certain treatments.
21 citations
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January 2003 in “Skin pharmacology and physiology” Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.
126 citations
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January 1987 in “Journal of The American Academy of Dermatology” The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.
51 citations
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January 2003 in “Hormone Research in Paediatrics” Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.
