Commonly Used Dermatology Drugs as Therapy for COVID-19
October 2020
in “
Actas Dermo-Sifiliográficas
”
TLDR Common dermatology drugs were considered but are controversial for COVID-19 treatment.
The document reviewed the potential use of common dermatological drugs as therapies for COVID-19, focusing on antimalarials, antiparasitics, antiandrogens, and melatonin. Antimalarials like hydroxychloroquine and chloroquine showed mixed results, with some studies indicating no significant benefit and others suggesting potential harm. Ivermectin showed promising in vitro results, but clinical evidence was lacking. Antiandrogens were noted for reducing viral entry into cells, with a study suggesting a link between androgens and COVID-19 severity in males. Melatonin was proposed for its anti-inflammatory and antioxidant properties. Overall, while these drugs had theoretical benefits, conclusive clinical evidence was insufficient, and further research was needed.