Diagnostic Significance of MIG and IP-10 Chemokines in Alopecia Areata

June 2025 in “ Medical Science Journal for Advance Research ”

Zinah Abbass Ali, Khawla A. Shemran, Hiba Resheed Behayaa

TLDR Higher levels of MIG and IP-10 may help diagnose and monitor Alopecia Areata.

The study investigated the serum levels of chemokines MIG and IP-10 in 60 patients with Alopecia Areata (AA) compared to 60 healthy controls. Results showed that AA patients had significantly higher levels of MIG (864.13 ± 201.08 pg/ml) and IP-10 (504.61 ± 122.2 pg/ml) than controls. MIG demonstrated a strong diagnostic capability with an AUC of 0.972, suggesting its potential as a biomarker for early diagnosis and monitoring of AA. Elevated levels of these chemokines indicate their possible involvement in the pathogenesis of AA.

View this study on medical.science.journal-asia.education →

Discuss this study in the Community →

Related Community Posts Join

6 / 1000+ results

community May have been mis-diagnosed for 10 years, self-investigation into AGA + AA Incognita (Defused Shedding)

in Treatment 1 upvotes 1 year ago

A 27-year-old male with AGA and diffused thinning has been using oral Minoxidil, Finasteride, Vitamin D, B12, Iron, and Ketoconazole shampoo. Despite a hair transplant and improved blood levels, he continues to experience hair loss and suspects a possible misdiagnosis of Alopecia Areata Incognita.

community IGFBP‐rP1 is a potential therapeutic target in androgenic alopecia

in Research/Science 13 upvotes 1 year ago

IGFBP‐rP1 shows potential for treating androgenic alopecia by influencing hair cycle transitions. Increasing IGF-1 levels may have similar effects to Minoxidil and 5-AR inhibitors in reducing hair loss.

community My Theory Of Androgenic Alopecia

in Research/Science 17 upvotes 4 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

community Most Recent Interesting Hairloss Studies: 10% Minox vs 5% Minox / Radio Rrequency Treatment for AA / Topical Ketoconazole / PRP+Minox vs Minox vs PRP / Alopecia as a systemic disease

in Treatment 91 upvotes 6 years ago

Treatments for hair loss, such as topical minoxidil, platelet-rich plasma therapy with or without minoxidil, ketoconazole, non-abative radio frequency, natural products, finasteride and cortexolone 17 alpha propionate. The post evaluates the efficacy and safety of these treatments in various studies.

community I am a dermatologist with a clinical interest in alopecia. AMA

in Will treatment work for me? 3 years ago

In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

community A new study by Deng and colleagues set out to explore differences between balding and non balding scalps...

in Research/Science 40 upvotes 4 years ago

Balding scalps have more androgen receptors, leading to increased TGF-beta, which causes blood vessel loss and hair follicle miniaturization. Blocking androgen signaling and TGF-beta may help prevent hair loss.

Similar Research

5 / 1000+ results