Differential Evolution of the Epidermal Keratin Cytoskeleton in Terrestrial and Aquatic Mammals
November 2018
in “
Molecular Biology and Evolution
”
Research cited in this study
16 / 16 results
research Types I and II Keratin Intermediate Filaments
Keratins are crucial for cell structure, growth, and disease risk.
research Evolution of Trichocyte Keratins
Hair keratins evolved from ancient proteins, diversifying through gene changes, crucial for forming claws and later hair in mammals.
research A Curated Catalog of Canine and Equine Keratin Genes
61 functional keratin genes were identified in dogs and horses, leading to updated gene annotations.
research Comparative Genomics Analyses of Alpha-Keratins Reveal Insights Into Evolutionary Adaptation of Marine Mammals
Marine mammals lost many α-keratin genes, aiding their adaptation to aquatic life by becoming hairless.
research A Keratin Scaffold Regulates Epidermal Barrier Formation, Mitochondrial Lipid Composition, And Activity
Keratin is crucial for skin barrier formation and affects mitochondrial function.
research Loss of Keratin K2 Expression Causes Aberrant Aggregation of K10, Hyperkeratosis, and Inflammation
Loss of keratin K2 causes skin problems and inflammation.
research Increased Rate of Hair Keratin Gene Loss in the Cetacean Lineage
Cetaceans lost hair genes to adapt to water.
research Beyond Expectations: The Role of Keratin Intermediate Filament Proteins in Epidermal Integrity
Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
research Keratin 79 Identifies a Novel Population of Migratory Epithelial Cells That Initiates Hair Canal Morphogenesis and Regeneration
Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.
research Recurrent Functional Divergence of Early Tetrapod Keratins in Amphibian Toe Pads and Mammalian Hair
Early tetrapod keratins evolved into toe pad proteins in amphibians and hair proteins in mammals.
research Against The Rules: Human Keratin K80
Keratin K80 is an ancient protein found in various tissues, important for cell structure and tissue differentiation.
research Identification of Reptilian Genes Encoding Hair Keratin-Like Proteins Suggests a New Scenario for the Evolutionary Origin of Hair
Reptiles have genes similar to hair proteins, suggesting hair's genetic origins predate mammals.
research The Human Keratins: Biology And Pathology
Keratins are crucial for cell stability, wound healing, and cancer diagnosis.
research Terrestrial Vertebrates Have Two Keratin Gene Clusters; Striking Differences in Teleost Fish
Terrestrial vertebrates have balanced keratin gene clusters, unlike teleost fish.
research Keratins of the Human Hair Follicle
More research is needed to understand how hair keratins work and their role in hair disorders.
research A Novel Mouse Type I Intermediate Filament Gene, Keratin 17n, Exhibits Preferred Expression in Nail Tissue
A new mouse gene, Keratin 17n, is mainly found in nail tissue and may explain why mice without Keratin 17 don't have nail issues.