Drug Repurposing Patent Applications July–September 2025

January 2025 in “ Drug repurposing ”

Hermann A. M. Mucke

TLDR New drug uses show promise but need more research.

This study reviews 16 notable drug repurposing patent applications from the third quarter of 2025, highlighting the diverse potential applications in pharmacy. Key examples include guanfacine for autonomic dysfunction, finerenone for low ovarian function and premature menopause, disulfiram for subarachnoid hemorrhage, entacapone for gout, lonidamine for herpes simplex virus-infected cornea, and lithium for reducing peripheral neuropathy from anticancer treatments. These applications are not yet issued patents and mostly lack peer-reviewed publications, but they provide valuable scientific and strategic insights.

View this study on drugrepocentral.scienceopen.com →

Discuss this study in the Community →

Research cited in this study

4 / 4 results

research Low-Dose Metformin and Profibrotic Signature in Central Centrifugal Cicatricial Alopecia

September 2024 in “JAMA Dermatology”

Low-dose metformin may help hair regrowth and reduce inflammation in CCCA.

research Hair Regrowth in Two Patients with Recalcitrant Central Centrifugal Cicatricial Alopecia After Use of Topical Metformin

24 citations , January 2020 in “JAAD Case Reports”

Topical metformin helped regrow hair in two women with a hard-to-treat scarring hair loss condition.

research Altered Polyamine Profiling in the Hair of Patients with Androgenic Alopecia and Alopecia Areata

4 citations , August 2019 in “Journal of Dermatology”

The conclusion is that balancing cost and carbon emissions in hybrid power systems is crucial, especially when high reliability is needed, but the model needs to consider all device efficiencies and distribution losses.

research Alopecia Areata: A Tissue-Specific Autoimmune Disease of the Hair Follicle

185 citations , August 2005 in “Autoimmunity Reviews”

Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.