The Association Between Dyslipidemia and Androgenic Alopecia: A Cross-Sectional Study From the Persian Guilan Cohort Study

July 2026 in “ Endocrine and Metabolic Science ”

Radin Behboodi, Hojat Eftekhari, Niloofar Faraji, Saman Maroufizadeh, Farahnaz Joukar, Fariborz Mansour‐Ghanaei

androgenetic alopecia dyslipidemia HDL androgenic alopecia AGA low HDL

TLDR In females, low HDL levels are linked to higher odds of hair loss.

This study, involving 10,520 adults from the PERSIAN Guilan Cohort Study, investigated the link between androgenetic alopecia (AGA) and dyslipidemia. While AGA was more prevalent in males (65.8%) than females (41.2%), dyslipidemia was more common in females. Overall, no significant association was found between AGA and dyslipidemia. However, in females, dyslipidemia was linked to higher odds of AGA, particularly with low HDL levels being a strong predictor. No significant associations were found in males, highlighting the importance of considering gender differences in clinical evaluations.

View this study on sciencedirect.com →

Discuss this study in the Community →

Research cited in this study

21 / 21 results

Potential Causal Relationship Between Extensive Lipid Profiles and Various Hair Loss Diseases: Evidence From Univariable and Multivariable Mendelian Randomization Analyses

research Potential Causal Relationship Between Extensive Lipid Profiles and Various Hair Loss Diseases: Evidence From Univariable and Multivariable Mendelian Randomization Analyses

April 2025 in “Journal of Cosmetic Dermatology”

Managing lipids may help treat hair loss.

research Androgenic Alopecia Is Associated With Higher Dietary Inflammatory Index And Lower Antioxidant Index Scores

August 2024 in “Frontiers in Nutrition”

Antioxidant-rich diets may reduce hair loss risk, while pro-inflammatory diets may increase it, especially in women.

research Androgenetic Alopecia: A Review

April 2024 in “Nigerian Postgraduate Medical Journal”

Androgenetic alopecia is a common hair loss condition influenced by various factors and linked to psychosocial and cardiovascular issues.

research The Biology and Genomics of Human Hair Follicles: A Focus on Androgenetic Alopecia

February 2024 in “International Journal of Molecular Sciences”

Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.

research Cardiovascular Risk in Patients With Scarring and Nonscarring Alopecias: Assessing the Current State of Evidence

September 2023 in “JEADV Clinical Practice”

People with common hair loss conditions may have a higher risk of heart disease and related health issues.

research Androgenetic Alopecia: Therapy Update

May 2023 in “Drugs”

There are many treatments for common hair loss, but more trials are needed to decide which are best.

research Comorbidities in Androgenetic Alopecia: A Comprehensive Review

September 2022 in “Dermatology and therapy”

Androgenetic alopecia is linked to heart disease, metabolic issues, and mental health problems.

research Systematic Review and Meta-Analysis of the Association Between Metabolic Syndrome and Androgenetic Alopecia

3 citations , December 2021 in “Acta dermato-venereologica”

People with androgenetic alopecia have a higher risk of metabolic syndrome.

research Understanding Causes of Hair Loss in Women

4 citations , May 2021 in “Dermatologic Clinics”

The conclusion is that hair loss in women is caused by a mix of hormonal, environmental, and genetic factors, and treatments should target these various causes.

research The Inflammatory Aspect of Male and Female Pattern Hair Loss

9 citations , November 2020 in “Journal of Inflammation Research”

Inflammation affects hair loss; anti-inflammatory treatments may help.

research Hormonal Regulation in Male Androgenetic Alopecia: Sex Hormones and Beyond - Evidence from Recent Genetic Studies

15 citations , June 2020 in “Experimental Dermatology”

Hormones and genes affect hair growth and male baldness.

research The Comparison of Blood Lipid Profile in Patients with and Without Androgenetic Alopecia

March 2020 in “Journal of the turkish academy of dermatology”

There's no significant link between blood fat levels and male pattern baldness.

research Female Pattern Hair Loss and Androgen Excess: A Report From the Multidisciplinary Androgen Excess and PCOS Committee

49 citations , February 2019 in “The Journal of Clinical Endocrinology and Metabolism”

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

research Dyslipidemia in Patients with Androgenetic Alopecia: Statins, Finasteride, or Both?

June 2017 in “Journal of The European Academy of Dermatology and Venereology”

Alopecia patients have higher heart disease risk; statins and finasteride may help.

research Classification of Male-Pattern Hair Loss

9 citations , January 2017 in “International Journal of Trichology”

No current system perfectly classifies male-pattern hair loss, indicating a need for a new system for better diagnosis and treatment.

research Lipid Profile in Patients with Androgenetic Alopecia: A Meta-Analysis

15 citations , October 2016 in “Journal of The European Academy of Dermatology and Venereology”

People with hair loss have worse cholesterol levels, possibly linking hair loss to heart problems.

research The Impact of Oxidative Stress on Hair

59 citations , November 2015 in “International Journal of Cosmetic Science”

Oxidative stress damages hair and contributes to aging, and managing it can help maintain hair health.

research Androgenetic Alopecia: New Insights Into the Pathogenesis and Mechanism of Hair Loss

33 citations , August 2015 in “F1000Research”

New model shows muscle affects hair loss differently in men and women.

research Androgenetic Alopecia, Metabolic Syndrome, and Insulin Resistance: Is There Any Association? A Case-Control Study

34 citations , January 2014 in “Indian Dermatology Online Journal”

Hair loss linked to metabolic issues and insulin resistance; early assessment may reduce future health risks.

research The Female Pattern Hair Loss: Review of Etiopathogenesis and Diagnosis

35 citations , January 2014 in “BioMed Research International”

Female pattern hair loss involves hormonal factors, genetics, and may be linked to low ferritin levels.

research Prevalence of Androgenetic Alopecia in China: A Community-Based Study in Six Cities

126 citations , January 2010 in “British Journal of Dermatology”

Baldness is more common in Chinese men than women, increasing with age, and is influenced by genetics.