Estetrol (E4) Prolongs Anagen in Healthy and Female Pattern Hair Loss Hair Follicles Ex Vivo

    July 2026 in “ Journal of the American Academy of Dermatology ”
    Alizée Le Riche, Sabrina Altendorf, Valérie Dion, Céline Gérard, Talveen Purba, Matthew Harries, Graham Dixon, Janin Edelkamp, Marta Bertolini
    TLDR Estetrol (E4) can help hair grow longer by extending its growth phase.
    The study investigates the effects of Estetrol (E4) on hair follicles, specifically its ability to prolong the anagen phase, which is the active growth phase of hair follicles. Conducted ex vivo, the research focused on both healthy hair follicles and those affected by female pattern hair loss. The findings suggest that E4 can effectively extend the anagen phase, indicating its potential as a therapeutic agent for promoting hair growth and addressing hair loss conditions.
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