Why Don't We Have More Effective Treatment for Keloids?

January 2010 in “ PubMed ”

Romana Čeović, Jasna Lipozenčić, Zrinka Bukvić Mokoš, Daška Štulhofer Buzina, Krešimir Kostović

TLDR We lack effective keloid treatments because their causes are not well understood.

The document discussed the challenges in treating keloids and hypertrophic scars, emphasizing that optimal treatment had not been established due to unclear pathogenetic mechanisms. It highlighted the importance of understanding these mechanisms at the molecular level to develop new therapies. Prevention was considered crucial in keloid therapy. The review presented both conventional and experimental treatments but noted the need for further research on safety, adverse effects, and efficacy. Due to the high recurrence rate of keloid scars, a follow-up period of at least 1 year was recommended to manage recurrences promptly and assess long-term success.

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community Why the cure is not yet found and why it is always 5 years away? Why no hopes on PP405, GT, KX, Hair cloning, AMP, etc, etc, etc

in Chat 18 upvotes 1 year ago

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community Some common misconceptions about why there have been no breakthroughs in treatments for so long and why a one and done cure is almost impossible.

in Treatment 53 upvotes 10 months ago

Developing new hair loss treatments is challenging due to the complexity and cost of trials, and a permanent cure is unlikely soon. Current treatments like Minoxidil and finasteride are used continuously because hair loss is progressive, and future possibilities include gene editing and hair cloning.

community How do we only have two treatments to combat hair loss at this point in time?

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The post discusses frustration over the limited and not always effective treatments for hair loss, mainly Minoxidil and Finasteride. The conversation includes mentions of potential new treatments like GT20029, HMI-115, CosmeRNA, KX-826, and microneedling, but also highlights the challenges of funding and prioritizing research in this area.

community Why Cant we just find an effective androgen receptor antagonist that works locally on the scalp?

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