The Effects of Acute Finasteride Treatment in Dopamine Transporter Knockout Mice and MK-801-Treated Mice
October 2019
in “
Asian College of Neuropsychopharmacology
”
Related Community Posts Join
6 / 1000+ resultscommunity Finasteride affects both 5a reductase and 5b reductase
6 upvotes 6 years ago Finasteride not only inactivates the 5a reductase enzyme but also affects the 5b reductase enzyme in a dose-dependent manner, which can impact sexual behavior and brain activity. The user experienced significant hair regrowth and side effects on 1mg of finasteride, which diminished after reducing the dose to 0.5mg, leading to no side effects and further hair improvement.
community Why is sexual functioning the main concern? Fin/dut can affect cognition and mood, arguably being more important
in Finasteride/Dutasteride 65 upvotes 1 month ago Finasteride and dutasteride can affect sexual function, cognition, and mood. Alternatives like minoxidil, pyrilutamide, and alfatradiol have varied effectiveness and side effects.
community Massive study on finasteride side effects released
in Finasteride/Dutasteride 83 upvotes 3 years ago The release of a study on 5a-reductase inhibitors (finasteride and dutasteride) which showed an increased risk of depression, dementia, decreased libido, and reduced semen load as potential side effects; discussion around other forms of hair loss treatments such as topical minoxidil, RU58841, or opting to accept baldness; and advice to consider professional help for deeper issues related to hair loss.
community How come Dut doesn’t cause more brain problems than fin if it inhibits Type 1 5AR?
in Finasteride/Dutasteride 22 upvotes 1 year ago Dutasteride and finasteride have similar risk profiles despite Dutasteride blocking more types of 5AR in the brain. Some users report no mood issues with either drug, and it is suggested that Dutasteride's larger molecular size may limit its ability to cross the blood-brain barrier.
community Possible transgenerational effects of finasteride use on male offspring? (STUDY)
in Research/Science 27 upvotes 1 month ago Finasteride may affect male offspring's fertility and hormonal balance, with debates on whether to discontinue use before conception. Some users report no issues, while others highlight the high doses used in rat studies.
community Fin effects on prostate sensation for MSM
in Finasteride/Dutasteride 4 upvotes 4 years ago Finasteride may affect prostate sensation and size, with some users reporting easier urination. Concerns exist about prostate shrinkage even at lower doses.
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1 / 1 resultsresearch Effect of the 5α-Reductase Enzyme Inhibitor Dutasteride in the Brain of Intact and Parkinsonian Mice
16 citations , October 2017 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Dutasteride may protect the brain in early Parkinson's disease.