Effects Of Keratin-Gelatin And Basic Fibroblast Growth Factor-Gelatin Composite Film On Open Wound Healing In Dogs And Cats

This study evaluated the wound healing properties of keratin-gelatin and bFGF-gelatin composite films in dogs and cats. Conducted on 36 dogs, the study found that keratin-gelatin composite film significantly improved wound healing, showing higher rates of epithelialization, wound contraction, and total healing compared to controls and bFGF-gelatin film. The keratin-gelatin film also facilitated early vascularization and acceptance of full-thickness skin mesh grafts, with 90-100% acceptance by Day 20 post-operation. Clinical cases involving 10 cats and 2 dogs confirmed its effectiveness. The study concluded that keratin-gelatin composite film was a superior and cost-effective biomaterial for wound healing, with potential commercial applications. Further research was suggested to explore different concentrations of these films.