Effects of Local and Systemic Medications on Eye Health: Adverse Reactions

The document examines the adverse effects of local and systemic medications on eye health, highlighting that systemic side effects from local eye treatments can impact the entire body, causing issues like fatigue, nausea, hair loss, and blood sugar fluctuations. Dry eye is the most common ocular side effect of systemic medications, often caused by antidepressants and antihistamines. Serious conditions like retinal detachment can result from fluoroquinolones. While many ophthalmic complications are temporary, serious adverse events are linked to neurotropic, immunotropic, and antitumor drugs, necessitating careful risk assessment and monitoring. The document underscores the importance of evaluating medication use in relation to ocular symptoms and the need for regular ophthalmologic monitoring, especially for patients on long-term medication or with pre-existing ocular conditions.