Efficacy and Safety of Topical Flutamide 1% Gel as an Adjunctive Therapy in the Treatment of Patients With Acne Vulgaris

A study involving 54 patients with mild to moderate acne vulgaris evaluated the efficacy and safety of topical Flutamide 1% gel as an adjunctive therapy. Over 8 weeks, Group A applied the gel twice daily, while Group B served as a control. Results showed a significant reduction in papules and a highly significant reduction in pustules. The study concluded that topical Flutamide 1% gel is a viable, efficient, and safe treatment option for acne vulgaris with minimal adverse effects, though further research with a larger patient group and longer duration is recommended.