The Efficacy and Psychoneuroimmunology Mechanism of Camouflage Combined With Psychotherapy in Vitiligo Treatment

The study investigated the efficacy of combining camouflage with psychotherapy in treating vitiligo, involving 149 patients in a non-randomized controlled trial. After 4 weeks, the intervention group, which received both treatments, showed significant improvements in quality of life compared to the control group, as measured by the Vitiligo Life Quality Index. Additionally, the intervention group experienced changes in serum levels of neuropeptides and cytokines, suggesting modulation of the psycho-neuro-endocrine-immune-skin system. These findings indicated that the combination of camouflage and psychotherapy could enhance vitiligo management by improving patients' quality of life and potentially influencing underlying biological mechanisms.