Efficacy of Hormonal Therapy Versus Non-Hormonal Therapy in Female Pattern Hair Loss: A Systematic Review

January 2026 in “ International Journal of Medicine in Developing Countries ”

Omar A Alsuwailem, Danah Alali, Dimah Aljameel, Tala Alashgar, Omnia Alali, Mohammed Almedires, Rawan Alanazi, Hanan Almeshal

hormonal therapy non-hormonal therapy female pattern hair loss FPHL PLLA microthread therapy minoxidil oral antiandrogens hair density hair thickness menstrual irregularities Rogaine

TLDR Both hormonal and non-hormonal therapies improve hair growth in women, but non-hormonal methods may be more effective with fewer side effects.

The systematic review compares the efficacy of hormonal versus non-hormonal therapies in treating Female Pattern Hair Loss (FPHL). The study concludes that hormonal therapies, particularly those targeting androgen pathways, show a higher efficacy in promoting hair regrowth and reducing hair loss compared to non-hormonal treatments. The review highlights the importance of personalized treatment plans, considering individual patient profiles and the underlying causes of FPHL. The findings suggest that while non-hormonal therapies can be beneficial, hormonal treatments may offer more significant improvements for many patients.

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