Efficacy of Serenoa Repens Lipido-Sterolic Extract Alone or in Combination with Propolis Polyphenols and Boswellia Serrata Extract Suppositories on PSA Level and Symptoms in Patients Affected by Lower Urinary Tract Disorders

    September 2025 in “ Archivio Italiano di Urologia e Andrologia ”
    U. Barbaresi, Mauro Dicuio, Federico Mineo Bianchi, Manola Marini, Francesca Quadrini, Santo Lupo, Roberta De Stefano
    TLDR Serenoa repens extract, alone or with other supplements, improves urinary symptoms and lowers PSA levels.
    The study evaluated the effects of Serenoa repens (Sr) extract, alone or combined with Phenolmicin P3 and Bosexil suppositories, on lower urinary tract symptoms (LUTS) and PSA levels in 509 patients with benign prostatic obstruction-related LUTS. After 6 months, data from 371 patients were analyzed. The results showed that Sr extract (320 mg daily) significantly alleviated LUTS. Additionally, combining Sr extract with a 20-day course of Phenolmicin P3 and Bosexil suppositories further improved LUTS and reduced PSA levels, indicating enhanced therapeutic efficacy.
    Discuss this study in the Community →