Comparison of the Efficacy of Topical Cetirizine 1% Versus Topical Minoxidil 5% Solution in the Treatment of Male Androgenetic Alopecia

    January 2025 in “ Mansoura Medical Journal ”
    Hadeer Samy Abd-Elfattah, Bothaina Mahrous Ghanem, Farid Abd-Elreheim Badria, Mohammed Samir Sultan
    TLDR Minoxidil is more effective than cetirizine for treating male hair loss.
    This study compared the efficacy and safety of topical cetirizine 1% and minoxidil 5% in treating male androgenetic alopecia (AGA) in 40 male patients. Results showed that minoxidil was more effective in improving hair diameter, terminal hair count, and reducing vellus hair count by weeks 16 and 24. Cetirizine also showed significant improvement, particularly by week 24, and had an excellent safety profile with no adverse events. Patient satisfaction was similar between the groups, though more patients in the minoxidil group reported "excellent" outcomes. Overall, both treatments were effective, with minoxidil being more effective.
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