Serum Epidermal Growth Factor Level and Its Relation to Severity of Alopecia Areata

January 2024 in “ International Journal of Applied Biochemistry and Molecular Biology. ”

Abd-El Aziz Ibrahim El-Taweel, Radwa Ibrahim Muhammad Muhammad El Metwally, Sara Mahmoud Hassan, Hanan Abd El-Razek Kamel

epidermal growth factor alopecia areata SALT scores EGF AA

TLDR Higher EGF levels are linked to more severe alopecia areata.

This study investigated the serum levels of epidermal growth factor (EGF) in 60 individuals, comprising 30 patients with alopecia areata (AA) and 30 healthy controls. The results showed that EGF levels were significantly higher in AA patients compared to controls and were positively correlated with the severity of the disease, as measured by SALT scores. This suggests that EGF could serve as a marker for AA severity and may play a causal role in its pathogenesis.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

MagicBold in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community New Treatments, and a Huge Group Buy with Lots of Research

in Research/Science 109 upvotes 2 years ago

A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

community The Real Cause Of Androgenetic Alopecia

in Research/Science 671 upvotes 1 year ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

nkrata in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth

in Research/Science 207 upvotes 1 year ago

PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.

community A meta analysis of 18 popular hair loss treatments. An 2022 guide on efficacy. From finasteride and minoxidil to caffeine shampoo, saw palmetto and biotin. 96 Scientific References included.

in Research/Science 101 upvotes 4 years ago

Most hair loss treatments are ineffective; only finasteride, dutasteride, and minoxidil show effectiveness.

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research Twenty Nail Dystrophy with Alopecia Areata in an Atopic Child

April 2019 in “International journal of research in dermatology”

A child with rough nails also had hair loss and allergies.