Engineered Extracellular Vesicles for Tissue Repair and Regeneration

    January 2024 in “ Burns & Trauma
    Yan Zhang, Dan Wu, Zhou Chen, Muran Bai, Yao Wan, Qing Zheng, Zhijin Fan, Xianwen Wang, Chunhua Yang
    TLDR Engineered extracellular vesicles can improve tissue repair and regeneration.
    Extracellular vesicles (EVs) are membrane-like structures secreted by cells that play a crucial role in tissue repair and regeneration by transferring proteins, lipids, and nucleic acids to target cells. Recent advancements in nanotechnology have enabled the engineering of EVs to enhance their therapeutic efficacy through gene editing, surface, and content modifications. This review discusses the mechanisms and potential of EVs in regenerative medicine, providing insights into their design and future development for tissue repair applications.
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