Environmental Enrichment Associated with the Promotion of Well-Being for Mice Kept in Animal Facilities

    January 2024 in “ Editora In Vivo eBooks ”
    Natália da Silva Dósea, Bárbara Alves de Brito Soledade, Hyago da Silva Medeiros Elidio, Jhônata Willy Rocha Coelho, Rita de Cássia dos Passos Ferraz da Silva, João Gabriel Regis Sobral, Tânia Regina Ribeiro de Melo, Wellington Hygino Ramos Souza, Leandro Thomaz Vilela, André Nunes de Sales, Isabele Barbieri dos Santos
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    TLDR Environmental enrichment improves lab mice welfare and research outcomes.
    The document emphasizes the importance of environmental enrichment for laboratory mice, which enhances their welfare by allowing natural behaviors and reducing stress. This practice aligns with the 3Rs principle (Replacement, Reduction, Refinement) and improves research outcomes by minimizing unnecessary use of mice. Enrichment strategies, such as using PVC tubes, absorbent paper, and auditory stimuli, improve cognitive functions, reduce stress, and enhance reproductive outcomes. The document also highlights the need for ongoing evaluation and maintenance of these strategies to ensure sustained benefits and a more natural environment for the mice.
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