TLDR A new accurate method was developed to measure Minoxidil and Aminexil in solutions.
The study presents a validated HPTLC method for estimating Minoxidil and Aminexil in topical solutions, using silica gel 60 F254 pre-coated TLC aluminium plates and a methanol: water (5:5) solvent system. Densitometric analysis at 254 nm revealed Rf values of 0.88 for Aminexil and 0.69 for Minoxidil, with linearity between 2-10 μg/spot for Minoxidil and 6-14 μg/spot for Aminexil. The method demonstrated high precision and accuracy, with %RSD below 2% and regression coefficients of 0.9983 for Minoxidil and 0.9993 for Aminexil, meeting ICH criteria.
August 2023 in “Journal of Cosmetic Dermatology” Some plants like spinach, broccoli, and matcha may boost the effectiveness of the hair growth drug minoxidil.
8 citations
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April 2019 in “Dermatologic Therapy” Tretinoin boosts minoxidil's effect on hair loss by increasing enzyme activity.
5 citations
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January 2018 in “Italian journal of dermatology and venereology” Minoxidil effectively stimulates hair growth in androgenetic alopecia.
1 citations
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January 2010 Mesotherapy is more effective than topical spray for female hair loss treatment.
269 citations
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August 2002 in “Journal of The American Academy of Dermatology” 5% minoxidil works better for hair growth and density, with minor irritation.
39 citations
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March 1987 in “Journal of The American Academy of Dermatology” Topical minoxidil is a safe and effective treatment for hair loss caused by androgenetic alopecia.
20 citations
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February 1985 in “Archives of Dermatology” Minoxidil helps hair regrowth, especially with more indeterminate hairs.
