Evaluation of Metal Nanoparticles Using ICP-OES in Hairs of Patients With Frontal Fibrosing Alopecia and Comparison With Control Group

This study investigated the concentrations of titanium, zinc, aluminum, and iron in the hair shafts of 30 patients with frontal fibrosing alopecia (FFA) compared to 30 controls. Using ICP-OES, it was found that FFA patients had significantly higher levels of these metals in their hair. The FFA group also reported more frequent use of haircare products, sunscreens, and cosmetics. Although no direct correlation was found between product use and metal concentrations in FFA patients, aluminum levels were linked to alopecia severity. The study suggests a potential association between metal exposure from products and FFA, recommending cautious reduction in the use of titanium- and zinc-containing products, but emphasizes the need for further research to confirm these findings.