Exosomes In Stroke Management: A Promising Paradigm Shift In Stroke Therapy

    December 2024 in “ Neural Regeneration Research
    Bo Wang, Pinzhen Chen, Wenyan Li, Zhi Chen
    TLDR Exosome therapy could revolutionize stroke treatment, but more research is needed for human use.
    Exosome therapy shows significant promise in stroke treatment, particularly in animal models, where it can reduce neuroinflammation, alleviate oxidative stress, and inhibit cell death. Exosomes, often derived from stem cells, can be modified to enhance their therapeutic effects, promoting angiogenesis and neural repair. Although preclinical research is promising, there is insufficient evidence for clinical application in stroke patients. The review highlights the potential of exosomes to transform stroke therapy and suggests new directions, such as targeting the ventricular-meningeal lymphatic system, for future research.
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