Levels of Extracellular ATP in Growth Zones of Arabidopsis Primary Roots Are Changed by Altered Expression of Apyrase Enzymes

    September 2025 in “ Plant Signaling & Behavior ”
    Greg Clark, Diana Vanegas, Ashley Cannon, Miranda Jankovik, Ryan Huang, Katherine A. Brown, Eric S. McLamore, Stanley J. Roux
    TLDR Apyrase enzymes control ATP levels in Arabidopsis root growth zones.
    The study examines the role of apyrase enzymes AtAPY1 and AtAPY2 in regulating extracellular ATP (eATP) levels in Arabidopsis primary roots. It was found that eATP concentrations are highest in the elongation zone of wild-type roots and vary inversely with the expression of these apyrases. Suppression of AtAPY1 and AtAPY2 led to increased eATP levels and inhibited root growth, while overexpression resulted in decreased eATP concentrations. The research suggests that AtAPY1 and AtAPY2 are crucial for maintaining low eATP levels necessary for normal root development, acting as a hormone-like signal in plants. Structural modeling supports their role by indicating potential ATP binding sites.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results