Factors Associated with the Severity of Female Pattern Hair Loss: A Retrospective Study

January 2026 in “ Aesthetic Plastic Surgery ”

Meiling Jian, Dan Zhang, Xingang Fu, Yuheng Cheng, Xiaoyu Sun, Zhibin Wang, Lin Li

This retrospective study of 289 patients with female pattern hair loss (FPHL) identified that the severity of FPHL is associated with the duration of the condition, with more severe cases (F2/3) being significantly older and having a longer duration than less severe cases (F1). Although lower levels of selenium, zinc, vitamin B9, and testosterone were noted in the more severe group, these were not independent risk factors after adjusting for demographic characteristics. The study concludes that elements, vitamins, and hormones do not predict FPHL severity, suggesting the need for larger prospective cohort studies to confirm these findings.

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research Effectiveness of Platelet-Rich Plasma in the Treatment of Androgenic Alopecia: A Meta-Analysis

August 2023 in “Aesthetic Plastic Surgery”

Platelet-rich plasma therapy helps increase hair density in male patients with hair loss but doesn't change hair thickness.

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June 2023 in “Clinica Chimica Acta”

Finasteride and dutasteride effectively reduce DHT in hair, which may help evaluate their treatment success for hair loss.

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11 citations , November 2022 in “Journal of Endocrinological Investigation”

Hormonal treatments can change hair and skin in transgender people, but may not fully achieve desired results.

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1 citations , October 2022 in “Current Opinion in Endocrinology, Diabetes and Obesity”

Female pattern hair loss is common in women with polycystic ovarian syndrome.

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research The Effects of Magnesium Supplementation on Abnormal Uterine Bleeding, Alopecia, Quality of Life, and Acne in Women With Polycystic Ovary Syndrome: A Randomized Clinical Trial

2 citations , August 2022 in “Reproductive Biology and Endocrinology”

Magnesium supplements improved quality of life for women with polycystic ovary syndrome, but didn't help with acne, hair loss, or abnormal bleeding.

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2 citations , May 2022 in “Journal of trace elements in medicine and biology”

Sodium pentaborate pentahydrate can increase hair growth and improve hair quality at certain doses.

research Transcriptome Analysis to Identify the Downstream Genes of Androgen Receptor in Dermal Papilla Cells

1 citations , January 2022 in “BMC Genomic Data”

The study found that androgen receptors in skin cells mainly affect the focal adhesion pathway and control the caveolin-1 gene, with implications for new treatments for related diseases.

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11 citations , October 2021 in “Journal of The European Academy of Dermatology and Venereology”

Topical finasteride is an effective and safer treatment for male hair loss.

research Analysis of Hair Steroid Hormone Concentrations at Different Parts of the Head by Liquid Chromatography-Tandem Mass Spectrometry

3 citations , October 2021 in “Clinica Chimica Acta”

Hormone levels in hair vary across the head, with the highest concentration of a key hormone linked to hair loss at the top.

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research Androgenetic Alopecia in Women and Men: Italian Guidelines Adapted from European Dermatology Forum/European Academy of Dermatology and Venereology Guidelines

4 citations , December 2020 in “Giornale italiano di dermatologia e venereologia”

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research Evaluation of Long-Term Efficacy of Finasteride in Korean Men with Androgenetic Alopecia Using the Basic and Specific Classification System

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Finasteride effectively treats hair loss in Korean men for at least 5 years, with V type responding better.

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79 citations , January 2017 in “Dermatology practical & conceptual”

Correcting nutrient deficiencies may help with hair loss, but the benefits of supplements without a deficiency are uncertain and could be harmful.

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Women with female pattern hair loss have lower Vitamin D3 levels.

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Lower hair zinc and copper levels found in Turkish males with hair loss; higher BMI linked to less hair zinc.

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29 citations , November 2012 in “Journal of The European Academy of Dermatology and Venereology”

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Familial factors affect hair loss types in Koreans, with M type in men, L type in women, and paternal factors influencing male hair loss more.

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Finasteride increases hair weight and count in men with hair loss, with best results after four years.