Finasteride, Pharmacogenomics, and Suicide Risk: A Public Health Concern
June 2026
in “
The Pharmacogenomics Journal
”
Research cited in this study
12 / 12 resultsresearch Finasteride Use and Suicide Attempts Through Self-Poisoning: A Case-Control Study
Finasteride does not increase the risk of suicide attempts.
research Signal Detection Between 5-Alpha Reductase Inhibitors and the Risk of Suicidality and Depression: An International Pharmacovigilance Analysis
Finasteride may increase the risk of suicidality and depression, especially in younger people.
research Finasteride Use: Evaluation of Depression and Suicide Risk
Finasteride use may increase depression and suicide risk, especially at 1 mg, so monitoring is advised.
research Association of 5α-Reductase Inhibitors With Depression and Suicide: A Mini Systematic Review and Meta-Analysis
Drugs for prostate enlargement and hair loss were not linked to increased risk of depression or suicide.
research Anxiety and Depression-Like Behaviour Following Short-Term Finasteride Administration Is Associated With Impaired Synaptic Plasticity and Cognitive Behaviour in Male Rats
Short-term finasteride use in male rats caused anxiety, depression, and memory problems.
research Food Administration and Not Genetic Variants Causes Pharmacokinetic Variability of Tadalafil and Finasteride
Food intake, not genetics, affects how the body processes tadalafil and finasteride.
research Neurosteroid Influence on Affective Tone
Endogenous neurosteroids may set a baseline mood.
research US Food and Drug Administration Warning Regarding Finasteride and Suicidal Ideation: What Should Urologists Know?
Urologists should screen for mental health issues before and during finasteride treatment.
research Suicidal Risk Associated With Finasteride Versus Dutasteride Among Men Treated for Benign Prostatic Hyperplasia: Nationwide Cohort Study
Finasteride may increase the risk of suicide or severe self-harm in men with mood disorders but not in the general population.
research Investigation of Suicidality and Psychological Adverse Events in Patients Treated With Finasteride
Finasteride may cause suicidal thoughts and mental side effects, especially in young people with hair loss.
research A Novel Finasteride 0.25% Topical Solution for Androgenetic Alopecia: Pharmacokinetics and Effects on Plasma Androgen Levels in Healthy Male Volunteers
New finasteride solution effectively reduces baldness-causing hormone, potentially with fewer side effects.
research In Vivo Investigation in Pigs of Intestinal Absorption, Hepatobiliary Disposition, and Metabolism of the 5α-Reductase Inhibitor Finasteride and the Effects of Coadministered Ketoconazole
Ketoconazole increases finasteride's effectiveness and lifespan in the body.
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research Failing Public Health Again? Analytical Review of Depression and Suicidality From Finasteride
Finasteride may increase depression and suicide risks, needing better safety checks and informed consent.
research Reframing the Discussion on Finasteride and Neuropsychiatric Safety
Finasteride is not proven to cause depression or suicide, and careful patient monitoring is advised.
research Suicidality Risks Associated with Finasteride, a 5-Alpha Reductase Inhibitor: An Evaluation of Real-World Data from the FDA Adverse Event Reports
Finasteride use may increase suicidality risk, especially in young men.
research Supplementary Material for: Finasteride and Suicide: A Postmarketing Case Series
The study explored a possible link between finasteride use and suicide.
research Finasteride: suicidality or psychological adverse events
Finasteride use linked to increased suicidality in patients under 45.