Analysis of Chemical-Quantum Interactions In Silico of Finasteride and Neurotransmitters and Their Role in Psychopathology

February 2025 in “ Ciencia Latina Revista Científica Multidisciplinar ”

Manuel González-Pérez, Giancarlo Landini, Rubén Abiud Villafuerte Salcedo

finasteride neurotransmitters alopecia benign prostatic hyperplasia carboxylic acid cortisol antioxidant amino acids nucleic acids Propecia

TLDR Finasteride can help with hair loss and prostate issues but may negatively affect mood and the nervous system.

This study investigates the chemical-quantum interactions of Finasteride (FNT) with neurotransmitters and its role in psychopathology using in silico methods. The research highlights both the beneficial effects of FNT in treating benign prostatic hyperplasia and alopecia, and its adverse effects on mood and the nervous system. Utilizing the Electron Transfer Coefficient theory and Hyperchem software, the study finds that FNT interferes with neurotransmitters, increasing psychopathological effects when it breaks down into a carboxylic acid analogous to Cortisol (ACTS), a strong oxidizing agent. Additionally, FNT is identified as a good antioxidant for amino acids and is not mutagenic to nitrogenous bases, including nucleic acids.

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community Male pattern baldness, and mental health

in Finasteride/Dutasteride 332 upvotes 2 years ago

A 48-year-old man has been using minoxidil for 15 years and considered finasteride but stopped due to potential side effects. He is concerned about his mental health and the impact of hair loss on self-image, and he encourages support among men experiencing hair loss.

community Finasteride does deplete important nuero-active steroids

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Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Possible Finasteride ban happening soon

in Finasteride/Dutasteride 165 upvotes 11 months ago

Concerns about a potential finasteride ban in the EU, possibly affecting the US, are discussed. Users doubt a ban, citing its widespread use and suggest alternatives like minoxidil and dutasteride.

community How many of you are on fin and how many are on dut

in Finasteride/Dutasteride 38 upvotes 1 year ago

Many people use finasteride and dutasteride for hair loss, with some switching due to cost or effectiveness. Minoxidil is also commonly used, and side effects like weaker erections or ball pain are reported by some.

community Topical Finasteride reduced my DHT more than Oral Dutasteride

in Finasteride/Dutasteride 42 upvotes 3 years ago

Treatments for hair loss, including the experiences of topical finasteride and oral dutasteride. It also discusses Pyrilutamide, 0.025% topical concentration, Minoxidil, RU58841, and 1% finasteride gel dosage.

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