The Effects of Finasteride on the Pituitary-Testicular Hormone Axis and Spermatogenesis in Rats
January 2005
Na Gj, Hwang Is, Oh Kj, Kim Kw, Kang Tw, Kwon Dd, Park Ks, Ryu Sb, Y I Park
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The conversation discusses the impact of finasteride on sperm, including potential side effects like decreased ejaculate volume and total sperm count. Users share experiences and concerns about fertility tests before and after starting finasteride.
Finasteride can reduce DHT in the genitalia, potentially causing side effects like reduced erections and penile fibrosis. Using PDE5 inhibitors like Tadalafil or Sildenafil may help maintain penile health and prevent fibrosis.
Finasteride may have positive effects by keeping testosterone levels higher, potentially maintaining youthfulness and physical performance as one ages. It could also help with conditions related to aging like andropause and sarcopenia without increasing estradiol levels.
Finasteride's impact on fertility is discussed, with users sharing experiences of conceiving while on the medication. Concerns about long-term safety are also mentioned.
Finasteride can affect hormone levels, potentially causing symptoms like puffy nipples and testicular pain, and may result in elevated prolactin and high testosterone. The user is seeking interpretation of these changes after taking finasteride.
Finasteride significantly increased testosterone levels for the user, with no major side effects except watery semen, which was resolved with zinc supplements. The user's hairline stopped receding and slightly improved.