The Effects of Finasteride on the Pituitary-Testicular Hormone Axis and Spermatogenesis in Rats
January 2005
Na Gj, Hwang Is, Oh Kj, Kim Kw, Kang Tw, Kwon Dd, Park Ks, Ryu Sb, Y I Park
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Finasteride may affect male offspring's fertility and hormonal balance, with debates on whether to discontinue use before conception. Some users report no issues, while others highlight the high doses used in rat studies.
The conversation discusses the impact of finasteride on sperm, including potential side effects like decreased ejaculate volume and total sperm count. Users share experiences and concerns about fertility tests before and after starting finasteride.
Finasteride can reduce DHT in the genitalia, potentially causing side effects like reduced erections and penile fibrosis. Using PDE5 inhibitors like Tadalafil or Sildenafil may help maintain penile health and prevent fibrosis.
Finasteride may have positive effects by keeping testosterone levels higher, potentially maintaining youthfulness and physical performance as one ages. It could also help with conditions related to aging like andropause and sarcopenia without increasing estradiol levels.
Finasteride can affect hormone levels, potentially causing symptoms like puffy nipples and testicular pain, and may result in elevated prolactin and high testosterone. The user is seeking interpretation of these changes after taking finasteride.
A man stopped taking finasteride, a hair loss treatment, to improve his fertility. His sperm count and motility increased after stopping the medication, but sperm shape did not change.