Breaking the Pattern: Frontal Fibrosing Alopecia in Men, a Case Series

This case series highlights two unusual instances of frontal fibrosing alopecia (FFA) in men, a condition typically seen in postmenopausal White women. The first case involved a 51-year-old White man who developed FFA following COVID-19 vaccination, with symptoms including scarring alopecia and perifollicular erythema. His son also developed oral lichen planus post-vaccination, suggesting a possible immune-mediated response. The second case was a 44-year-old South Asian man with a misdiagnosed facial rash, later confirmed as FFA with prominent facial papules. These cases underscore the rarity of FFA in men, its potential link to immune triggers like vaccines, and the need for further research into its genetic and environmental causes. A 2023 study identified two genes associated with male FFA, distinct from those in women, indicating different pathogenesis and potential treatment strategies.