Genome-Based Analysis of the Genetic Pattern of Black Sheep in Qira Sheep

The study investigated the genetic basis of black wool formation in Qira sheep by analyzing 123 adult ewes with different coat colors (black, brown, and grey). Using Illumina Ovine SNP 50K chip data, the researchers found that the genetic structure of the sheep populations did not differ by wool color. They identified 71 SNPs associated with black wool traits, with significant associations found in the TYRP1, PARD3, and CDH2 genes. Notably, three mutations in the exon 1 region of the TYRP1 gene were linked to coat color variation. These findings provide a foundation for selecting black sheep lines and conserving the breed.